(R)-Glycidyl Butyrate: Key Properties & Sourcing Guide

 

Learn about (R)-Glycidyl Butyrate: Trusted Supplier Insights and Uses

Discover the properties of (R)-Glycidyl Butyrate, its CAS number and reliable sourcing options. Learn how AgexPharma delivers quality. Get expert insights, read now!

Introduction

Finding an epoxide for pharmaceutical or fine-chemical synthesis requires reliable data and a trusted supplier. This short guide provides what you need: specifications, actual uses in real processes and useful sourcing advice. It helps you choose the material and work with a dependable partner, with confidence.

Table of Contents

• Understanding (R)-Glycidyl Butyrate

• Key Properties and Specifications

• Applications in Industry

• Choosing the Right Supplier

• Safety and Handling Best Practices

• FAQs

• Conclusion

Understanding (R)-Glycidyl Butyrate

(R)-Glycidyl Butyrate is a compound that contains an epoxide ring. (R)-Glycidyl Butyrate is useful as an intermediate in many organic synthesis steps. The unique stereochemistry of (R)-Glycidyl Butyrate makes it especially valuable for routes. This is important when building molecules that have a defined three-dimensional shape.

In practice (R)-Glycidyl Butyrate acts as a precursor to glycidol and, to functionalized intermediates. (R)-Glycidyl Butyrate is commonly used in situations where optical purity and controlled reactivity're non-negotiable.

Key Properties and Specifications

When reviewing specifications pay attention to identity, purity and physical constants. These factors directly affect performance during synthesis. How well the compound works in later processing steps.

• CAS Number: 60456-26-0

• Molecular Formula: C₇H₁₂O₃

• Molecular Weight: 144.17 g/mol

• Appearance: Colorless to slightly yellow liquid

• Purity: Typically ≥98% (GC)

• Boiling Point: ~90°C at 19 mmHg

• Density: ~1.032 g/mL at 20°C

• Refractive Index: n₂₀/D ≈ 1.428

• Optical Rotation: [α]₂₅/D ≈ −31° (neat)

• Flash Point: ~84–85°C

• Solubility: Soluble in chloroform ethyl acetate; insoluble in water

Storage under atmosphere at 2–8 °C helps maintain stability and minimize hydrolysis.

Applications in Industry

This epoxide intermediate is widely used in:

• Pharmaceutical synthesis: Building side chains and oxazolidinone cores (for example antibiotics such as linezolid).

• Fine chemicals: Preparing glycidol, glycerol derivatives glycidyl ethers and amines.

• Polymer additives: Acting as an epoxy resin diluent and stabilizer in vinyl polymer manufacturing.

• Hydraulics: Serving as an additive, in oil and synthetic hydraulic fluids.

Its reactivity profile supports ring-opening transformations, esterifications and nucleophilic substitutions under controlled conditions.

Choosing the Right Supplier

Quality and consistency depend on the partner you choose. Here is how to check a vendor

• Documentation: Ask for COA, MSDS and method of analysis (for example GC purity).

• Batch traceability: Make sure there is tracking at the lot level and stability data available.

• Scale and lead time: Check that the supplier can handle the amounts you need and meet the deadlines.

• Support: Choose suppliers who can give advice on handling and compatibility.

When looking at an (R)-Glycidyl Butyrate supplier focus on transparency following rules and regulations and having test results that're the same each time. For needs working directly with an (R)-Glycidyl Butyrate manufacturer can make things cheaper and more reliable.

Companies like AgexPharma specialize in pharma-grade intermediates, with quality control steps which're good for work that needs to follow GMP rules.

Safety and Handling Best Practices

Treat this epoxide with epoxide precautions:

• PPE: Gloves, goggles and lab coat; work in a fume hood.

• Inert handling: Use inert conditions to limit moisture exposure.

• Storage: Keep closed under nitrogen at 2–8, °C.

• Spill response: Absorb with material; avoid water contact where possible.

Always consult the SDS before use and align with your sites EHS procedures.

Frequently Asked Questions

1. What is the CAS number for (R)-Glycidyl Butyrate?

The (R)-Glycidyl Butyrate CAS number is 60456-26-0.

2. What purity levels are typical for synthesis-grade material?

Most suppliers offer ≥98% purity by GC with rotation around −31° (neat).

3. How should it be stored to maintain stability?

Store under an atmosphere (nitrogen) tightly sealed at 2–8°C.

4. What are common applications in pharma?

Its used to build intermediates, including oxazolidinone antibiotics and glycidol derivatives.

5. How do I verify supplier quality?

Ask for COA, MSDS, GC method details and batch traceability; prefer vendors, with pharma-grade QC.

Conclusion

(R)-Glycidyl Butyrate is a chiral building block used in the pharmaceutical and fine-chemical industries. It is important to know the properties of (R)-Glycidyl Butyrate. It is also important to check the (R)-Glycidyl Butyrate CAS number. When working with a supplier of (R)-Glycidyl Butyrate you can lower the risk. Make the development process faster.

Ready to source with confidence? Explore pharma-grade intermediates, at AgexPharma. Request specifications today.